Fig. 4

The protein levels of total IgA, IgA1, IgA2, and TGF-β in sinonasal tissue homogenates of CRSwNP, CRSsNP, and control groups. The concentrations of total IgA and IgA1 in tissue homogenates of CRSwNP patients were significantly increased in comparison to CRSsNP and control groups. There is no difference in the protein level of IgA2 in three groups. The data are represented by column and the Kruskal–Wallis test was used for the statistical analyses. *P < 0.05; **P < 0.01; ****P < 0.0001 CRSsNP chronic rhinosinusitis without nasal polyps, CRSwNP chronic rhinosinusitis with nasal polyps