Local eosinophils are associated with increased IgA subclass levels in the sinonasal mucosa of chronic rhinosinusitis with polyp patients

Table 3 General histologic results of control, CRSsNP, and CRSwNP groups

	Control	CRSsNP	CRSwNP	Control vs. CRSsNP	Control vs. CRSwNP	CRSwNP vs. CRSsNP
Neutrophils	0.5 (0.5–1.5)	2 (1–4.5)	5 (2.5–9.25)	0.023	<0.001	0.85
Eosinophils	0.5 (0.5–1)	11.5 (4.5–17.5)	23.25 (6.75–36)	< 0.001	< 0.001	0.1
Mononuclear cells	9.5 (6–13)	13.5 (8.5–19)	26 (15–35)	0.275	< 0.001	0.007
Goblet cells	13.5 (10.5–19)	12.5 (10–15.5)	7.5 (5–14.25)	0.078	0.008	0.71
Mucosal gland	22.5 (17.5–32)	15.5 (10–20)	13.5 (7.5–27.5)	0.702	0.013	0.005
Inflammatory cells	12 (8.5–18.5)	29.75 (17.25–43)	63.75 (48–88.75)	0.031	< 0.001	0.002

Values are expressed as medians (IQR). The Mann-Whitney U test was used for unpaired comparisons
CRSsNP Chronic rhinosinusitis without nasal polyps, CRSwNP Chronic rhinosinusitis with nasal polyps
P < 0.05 was considered statistically significant. Italics P values show significant results (<0.05)

ISSN: 1710-1492