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Table 4 Immunohistochemistry results of control, CRSsNP and CRSwNP groups

From: Local eosinophils are associated with increased IgA subclass levels in the sinonasal mucosa of chronic rhinosinusitis with polyp patients

 ControlCRSsNPCRSwNPControl vs. CRSsNPControl vs. CRSwNPCRSwNP vs. CRSsNP
Total IgA LP3 (2–4)6.5 (5–8.5)8 (5–13.5)< 0.001< 0.0010.77
IgA2 LP0 (0–0)1 (1–1)1 (0–2)0.023< 0.0010.721
IgA1 LP2.5 (2–3)6.5 (5–8.5)6.5 (4–10)<0.001<0.0010.82
Total IgA EP1 (1–1)1 (0.5–2)2 (1–3)0.340.0020.122
IgA2 EP0 (0–0)0 (0–0.5)0 (0–1)0.10.110.1
IgA1 EP1 (1–1)1 (0.5–2)2 (1–2)0.340.0010.11
CD201 (1–2)5.5 (3–8)14 (6.5–34.5)0.001< 0.0010.134
CD1384 (2–5)5 (2–7)10.5 (5–33.5)0.327< 0.0010.009
  1. Values are expressed as medians (IQR). Mann-Whitney U test was used for unpaired comparisons
  2. CRSsNP Chronic rhinosinusitis without nasal polyps, CRSwNP Chronic rhinosinusitis with nasal polyps, LP Lamina propria, EP Epithelium
  3. P < 0.05 was considered statistically significant. Italic P values show significant results (<0.05)