Local eosinophils are associated with increased IgA subclass levels in the sinonasal mucosa of chronic rhinosinusitis with polyp patients

Table 5 General histologic results of eosinophilic and non-eosinophilic CRSwNP subgroups

	ENP	N-ENP	ENP vs. N-ENP	ENP vs. CRSsNP	N-ENP vs. CRSsNP
Neutrophils	5 (2.5–9.75)	3.5 (1–6.5)	0.267	0.005	0.2
Eosinophils	35 (24.5–45)	6 (5–7)	< 0.001	< 0.001	0.347
Mononuclear cells	30 (15–33.75)	21 (15–35)	0.745	0.007	0.016
Goblet cells	7.5 (5.25–13)	6 (5–135.5)	0.673	0.1	0.152
Mucosal gland	19 (7.5–28)	12 (7.5–15)	0.239	0.5	0.437
Inflammatory cells	73 (62–101)	33.5 (31.5–54)	< 0.001	< 0.001	0.152

Values are expressed as median (IQR). Mann-Whitney U test was used for unpaired comparisons
CRSsNP Chronic rhinosinusitis without nasal polyps, ENP Eosinophilic chronic rhinosinusitis with nasal polyps, N-ENP Non-eosinophilic chronic rhinosinusitis with nasal polyps
P < 0.05 was considered statistically significant. Italic P values show significant results (<0.05)

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