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Table 2 Number of individual published mentions of HAE-C1INH and AD comorbidity grouped by MedDRA v21.0 high level terms

From: Co-occurrence between C1 esterase inhibitor deficiency and autoimmune disease: a systematic literature review

High level MedDRA term Number of HAE comorbid AD mentions
 Lupus erythematosus and associated conditions 52
  Systemic lupus erythematosus 30
  Lupus 7
  Discoid lupus 8
  Lupus-like disease 4
  Cutaneous lupus 2
  Drug-induced lupus 1
 Endocrine autoimmune disorders 21
  Thyroid diseases 21
 Glomerulonephritis and nephrotic syndrome 16
  Glomerulonephritis 16
 Gastrointestinal inflammatory conditions 16
  Crohn’s disease 8
  Celiac disease 7
  Ulcerative colitis 1
 Rheumatoid arthritis and associated conditions 11
  Rheumatoid arthritis 11
 Eye, salivary gland and connective tissue disorders 10
  Sjogren’s syndrome 7
  Sicca syndrome 1
  Mixed connective tissue disease 2
 Immune and associated conditions not elsewhere classified 5
  Psoriasis 3
  Psoriatic arthritis 2
  1. Groups with ≥ 5 mentions are shown
  2. AD autoimmune disease, C1-INH C1 esterase inhibitor, HAE hereditary angioedema, MedDRA Medical Dictionary for Regulatory Activities