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Table 2 Adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for atopic dermatitis and food allergy according to season of birth

From: Season of birth is associated with increased risk of atopic dermatitis in Japanese infants: a retrospective cohort study

 

Atopic dermatitis

Food allergy

No. of events

Person-months of follow-up

Crude HR (95% CI)

Adjusted HRa (95% CI)

No. of events

Person-months of follow-up

Crude HR (95% CI)

Adjusted HRb (95% CI)

Spring

86

1056

1.29 (0.94–1.78)

1.43 (1.04–1.98)

7

1808

1.05 (0.35–3.12)

0.95 (0.32–2.85)

Summer

68

1077

1.00

1.00

6

1632

1.00

1.00

Autumn

117

671

2.18 (1.61–2.95)

2.67 (1.96–3.63)

6

1663

1.02 (0.33–3.16)

0.98 (0.32–3.07)

Winter

94

855

1.60 (1.17–2.19)

1.42 (1.03–1.95)

4

1712

0.64 (0.18–2.25)

0.58 (0.16–2.10)

  1. HR hazard ratio, CI confidence interval
  2. aAdjustment for sex, birthweight, siblings, cesarean birth, and use of emollient at 1 month of age
  3. bAdjustment for sex, birthweight, siblings, atopic dermatitis at 1 month, and use of emollient at 1 month of age