From: Anaphylaxis to three humanized antibodies for severe asthma: a case study
A. SPT after benralizumab treatment. | Wheal (mm)/flare (mm) |
---|---|
Histamine | 7 × 7/22 × 22 |
Saline | 1 × 1/1 × 1 |
Polysorbate 20 | 2 × 2/2 × 2 |
B. SPT after omalizumab treatment. | Wheal (mm)/flare (mm) |
---|---|
Benralizumab | 4 × 4/4 × 4 |
Mepolizumab | 2 × 2/2 × 2 |
Omalizumab | 2 × 2/2 × 2 |
C. DLST after omalizumab treatment. | % |
---|---|
Benralizumab | 232 |
Mepolizumab | 78 |
Omalizumab | 117 |