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Fig. 4 | Allergy, Asthma & Clinical Immunology

Fig. 4

From: Inhalation of nebulized Mycobacterium vaccae can protect against allergic bronchial asthma in mice by regulating the TGF-β/Smad signal transduction pathway

Fig. 4

HE staining and PAS staining results of the lung tissue (×200). The lungs in the normal control group mice showed complete airway epithelium mucosa, the cilia were ordered, the basilar membranes and smooth muscle were thin, there was no inflammatory cell infiltration around the vessels and airways, there were no mucus secretion (A1 and A2). In the asthma control group, there was cellular swelling of the airway epithelia, the plicae mucosae were increased, cilia were disordered, the bronchial mucous membranes were broken, many inflammatory cells infiltrated the bronchioles, the smooth muscle showed hyperplasia, PAS staining showed generous mucus and mucus plugs, (B1 and B2). In the M. vaccae prevention group, the airway lumen was unobstructed and the epithelia lined up inorder; PAS staining showed no mucus secretion (C1 and C2)

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