Table 1 Clinical and laboratory characteristics of subjects in two group
Variable | Patients (n = 30) | Controls (n = 30) | P value |
|---|---|---|---|
Age, median (IQR), years | 7.5 (5–9.25) | 7 (5.75–11) | 0.77 |
Sex, male/female | 17/13 | 14/16 | 0.606 |
Allergen (positive/negative) | 21/9 | 6/24 | < 0.001 |
Eosinophils in blood, average (95% CI) | 2.97 (2.662–3.285) | 2.207 (2.032–2.381) | < 0.001 |
FEV1.0/FVC% | 75.3 ± 12.03 | 91.2% ± 8.76 | < 0.001 |
IDO in sputum, average (95% CI) | 5.442 (4.950–5.935) | 8.912 (8.398–9.426) | < 0.001 |
IDO in blood, average (95% CI) | 3.136 (2.787–3.485) | 4.12 (3.638–4.603) | 0.001 |
Treg, average ± SD (%) | 3.97 ± 2.052 | 5.69 ± 2.434 | < 0.01 |
Th17/Treg, average ± SD | 0.45 ± 0.430 | 1.04 ± 0.666 | 0.002 |