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Table 1 Clinical and laboratory characteristics of subjects in two group

From: Th17/Treg imbalance is associated with reduced indoleamine 2,3 dioxygenase activity in childhood allergic asthma

Variable Patients (n = 30) Controls (n = 30) P value
Age, median (IQR), years 7.5 (5–9.25) 7 (5.75–11) 0.77
Sex, male/female 17/13 14/16 0.606
Allergen (positive/negative) 21/9 6/24 < 0.001
Eosinophils in blood, average (95% CI) 2.97 (2.662–3.285) 2.207 (2.032–2.381) < 0.001
FEV1.0/FVC% 75.3 ± 12.03 91.2% ± 8.76 < 0.001
IDO in sputum, average (95% CI) 5.442 (4.950–5.935) 8.912 (8.398–9.426) < 0.001
IDO in blood, average (95% CI) 3.136 (2.787–3.485) 4.12 (3.638–4.603) 0.001
Treg, average ± SD (%) 3.97 ± 2.052 5.69 ± 2.434 < 0.01
Th17/Treg, average ± SD 0.45 ± 0.430 1.04 ± 0.666 0.002
  1. IDO unit: %; Eosinophils unit: %
  2. IDO indoleamine 2,3-dioxygenase, FEV1.0/FVC% maximum expiratory rate in the first second, IQR interquartile range, CI confidence interval