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Table 4 Genetic risk score analysis between SNVs in CYP2R1, CYP24A1 and 25(OH)D serum levels

From: Genetic polymorphisms in vitamin D pathway influence 25(OH)D levels and are associated with atopy and asthma

 

CYP2R1

CYP24A1

25(OH)D serum concentration

rs10500804

rs12794714

rs3886163

Frequency

β (CI 95%)a

*p value

1

T

G

C

0.6016

00

–

2

T

G

T

0.1042

− 1.41 (− 3.25 to 0.42)

0.130

3

G

A

C

0.2513

− 1.24 (− 2.42 to − 0.06)

0.040

4

G

A

T

0.0422

− 3.29 (− 6.19 to − 0.39)

0.027

  1. aLinear regression B coefficient adjusted by sex, age and individual genetic ancestry
  2. *Snpstat p value
  3. In italic statistically significant association, in italic borderline association
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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