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Table 6 Summary of studies detecting antithyroid peroxidase (anti-TPO) antibodies in subjects with CSU and healthy controls

From: Presence of positive skin prick tests to inhalant allergens and markers of T2 inflammation in subjects with chronic spontaneous urticaria (CSU): a systematic literature review

Reference (author, year) Region Definition of CSU in weeks Number of CSU patients undergoing testing Number of healthy controls undergoing testing % prevalence of anti-TPO antibody in study group % prevalence of anti-TPO antibody in control group Number of antihistamine (AH) and/or systemic corticosteroid (SC)-free days
Verneuil, 2004 [103] France 45 30 17.8 3.3 Not stated
Gangemi, 2009 [104] Italy > 6 95 0 26.3 Not stated
Nuzzo, 2011 [105] Italy > 6 54 108 22.2 1.9 Not allowed
Alpay, 2013 [106] Turkey > 6 50 50 12 4 3 (AH)
Cho, 2013 [107] United States > 6 27 20 11.1 20.0 Not stated
Wan, 2013 [108] Taiwan > 6 60 40 8.3 0 Allowed (AH)
Yadav, 2013 [109] India > 6 80 0 17.5 3 (AH), 21 (SC)
Kim, 2016 [110] Korea > 6 184 0 13.6 Not stated
Czarnecka-Operacz, 2017 [111] Poland > 6 145 35 15.9 Not stated
Kasumagic-Halilovic, 2017 [112] Bosnia and Herzegovina > 6 70 70 30 1.4 Not stated
Schoepke, 2019 [98] Multinational > 6 182 0 20.9 3 (AH), 28 (SC)
  1. Anti-TPO antithyroid peroxidase, AH antihistamine, SC systemic corticosteroids