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Table 6 Summary of studies detecting antithyroid peroxidase (anti-TPO) antibodies in subjects with CSU and healthy controls

From: Presence of positive skin prick tests to inhalant allergens and markers of T2 inflammation in subjects with chronic spontaneous urticaria (CSU): a systematic literature review

Reference (author, year)

Region

Definition of CSU in weeks

Number of CSU patients undergoing testing

Number of healthy controls undergoing testing

% prevalence of anti-TPO antibody in study group

% prevalence of anti-TPO antibody in control group

Number of antihistamine (AH) and/or systemic corticosteroid (SC)-free days

Verneuil, 2004 [103]

France

45

30

17.8

3.3

Not stated

Gangemi, 2009 [104]

Italy

> 6

95

0

26.3

Not stated

Nuzzo, 2011 [105]

Italy

> 6

54

108

22.2

1.9

Not allowed

Alpay, 2013 [106]

Turkey

> 6

50

50

12

4

3 (AH)

Cho, 2013 [107]

United States

> 6

27

20

11.1

20.0

Not stated

Wan, 2013 [108]

Taiwan

> 6

60

40

8.3

0

Allowed (AH)

Yadav, 2013 [109]

India

> 6

80

0

17.5

3 (AH), 21 (SC)

Kim, 2016 [110]

Korea

> 6

184

0

13.6

Not stated

Czarnecka-Operacz, 2017 [111]

Poland

> 6

145

35

15.9

Not stated

Kasumagic-Halilovic, 2017 [112]

Bosnia and Herzegovina

> 6

70

70

30

1.4

Not stated

Schoepke, 2019 [98]

Multinational

> 6

182

0

20.9

3 (AH), 28 (SC)

  1. Anti-TPO antithyroid peroxidase, AH antihistamine, SC systemic corticosteroids