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Table 2 Participant clinical features by outcome of food challenge

From: Change in exhaled nitric oxide during peanut challenge is related to severity of reaction

  Tolerant (n = 15) Clinical allergy (n = 21) p-value
Age (years)
 Median (min, max) 10.2 (7.5, 17.2) 11.4 (5.1, 16.5) 0.9054
Gender (%)
 Males 12 (80) 10 (48) 0.0833
Previous peanut ingestion (%)
 Total 12 (80) 16 (76) > 0.9999
Previous adrenaline usage (%)
 Total 1 (7) 0 (0) 0.4167
Other food allergy (%)
 Total 2 (13) 5 (24) 0.6738
Household smokers (%)
 Total 3 (20) 4 (19) > 0.9999
Allergic rhinitis (%)
 Total 11 (73) 15 (71) > 0.9999
AR severity for those with AR-max = 4a
 Median (min, max) 1 (1, 4) 2 (1, 4) 0.6860
Eczema ever (%)
 Total 11 (73) 18 (86) 0.4178
Eczema active treatment (%)
 Total 3 (20) 5 (24) > 0.9999
SCORAD for those with visible eczema
 Median (min, max) 15.3 (10.7, 36.0) 14.7 (6.0, 32.5) 0.6429
Asthma ever (%)
 Total 8 (53) 7 (33) 0.3104
Current preventer (%)
 Total 4 (27) 4 (19) 0.6940
Current reliever (%)
 Total 6 (40) 4 (19) 0.2600
Exercise related wheeze or dry nocturnal cough (%)b
 Total 8 (53) 8 (38) 0.4996
Peanut SPT (mm)
 Median (min, max) 3.5 (0.0, 10.0) 7.0 (4.0, 9.0) 0.0001
Peanut sIgE (kU/L)
 Median (min, max) 0.50 (0.01, 26.80) 3.20 (0.10, 92.00) 0.0054
Ara h2 sIgE (kU/L)
 Median (min, max) 0.13 (0.00, 1.00) 1.60 (0.08, 70.30) 0.0002
FeNO (NIOX VEROc) (p.p.b)
 Median (min, max) 22 (5, 49) 29 (5, 97) 0.2662
Percent predicted FEV1d
 Median (min, max) 100 (86, 121) 102 (72, 124) 0.7910
Percent predicted FVCd
 Median (min, max) 104 (88, 128) 100 (70, 119) 0.4147
Percent predicted FEV1/FVCd
 Median (min, max) 95 (82, 114) 102 (93, 111) 0.0692
  1. AR allergic rhinitis, SCORAD SCORing Atopic Dermatitis SPT skin prick test, sIgE specific Immunoglobulin E, FeNO fraction exhaled nitric oxide, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity
  2. a AR severity: 1 = intermittent mild, 2 = intermittent mod-severe, 3 = persistent mild, 4 = persistent mod-severe
  3. b Exercise related wheeze or dry nocturnal cough, not related to respiratory infection in the previous 12 months
  4. c Only 33 patients were able to have FeNO measured via NIOX VERO (14 tolerant, 19 clinical allergy)
  5. d Only 21 patients were able to have spirometry performed (6 tolerant, 15 clinical allergy)
  6. Italic text indicates significant p value (less than 0.05)