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Table 2 Participant clinical features by outcome of food challenge

From: Change in exhaled nitric oxide during peanut challenge is related to severity of reaction

 

Tolerant (n = 15)

Clinical allergy (n = 21)

p-value

Age (years)

 Median (min, max)

10.2 (7.5, 17.2)

11.4 (5.1, 16.5)

0.9054

Gender (%)

 Males

12 (80)

10 (48)

0.0833

Previous peanut ingestion (%)

 Total

12 (80)

16 (76)

> 0.9999

Previous adrenaline usage (%)

 Total

1 (7)

0 (0)

0.4167

Other food allergy (%)

 Total

2 (13)

5 (24)

0.6738

Household smokers (%)

 Total

3 (20)

4 (19)

> 0.9999

Allergic rhinitis (%)

 Total

11 (73)

15 (71)

> 0.9999

AR severity for those with AR-max = 4a

 Median (min, max)

1 (1, 4)

2 (1, 4)

0.6860

Eczema ever (%)

 Total

11 (73)

18 (86)

0.4178

Eczema active treatment (%)

 Total

3 (20)

5 (24)

> 0.9999

SCORAD for those with visible eczema

 Median (min, max)

15.3 (10.7, 36.0)

14.7 (6.0, 32.5)

0.6429

Asthma ever (%)

 Total

8 (53)

7 (33)

0.3104

Current preventer (%)

 Total

4 (27)

4 (19)

0.6940

Current reliever (%)

 Total

6 (40)

4 (19)

0.2600

Exercise related wheeze or dry nocturnal cough (%)b

 Total

8 (53)

8 (38)

0.4996

Peanut SPT (mm)

 Median (min, max)

3.5 (0.0, 10.0)

7.0 (4.0, 9.0)

0.0001

Peanut sIgE (kU/L)

 Median (min, max)

0.50 (0.01, 26.80)

3.20 (0.10, 92.00)

0.0054

Ara h2 sIgE (kU/L)

 Median (min, max)

0.13 (0.00, 1.00)

1.60 (0.08, 70.30)

0.0002

FeNO (NIOX VEROc) (p.p.b)

 Median (min, max)

22 (5, 49)

29 (5, 97)

0.2662

Percent predicted FEV1d

 Median (min, max)

100 (86, 121)

102 (72, 124)

0.7910

Percent predicted FVCd

 Median (min, max)

104 (88, 128)

100 (70, 119)

0.4147

Percent predicted FEV1/FVCd

 Median (min, max)

95 (82, 114)

102 (93, 111)

0.0692

  1. AR allergic rhinitis, SCORAD SCORing Atopic Dermatitis SPT skin prick test, sIgE specific Immunoglobulin E, FeNO fraction exhaled nitric oxide, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity
  2. a AR severity: 1 = intermittent mild, 2 = intermittent mod-severe, 3 = persistent mild, 4 = persistent mod-severe
  3. b Exercise related wheeze or dry nocturnal cough, not related to respiratory infection in the previous 12 months
  4. c Only 33 patients were able to have FeNO measured via NIOX VERO (14 tolerant, 19 clinical allergy)
  5. d Only 21 patients were able to have spirometry performed (6 tolerant, 15 clinical allergy)
  6. Italic text indicates significant p value (less than 0.05)