Predominant patterns of β-lactam hypersensitivity in a single German Allergy Center: exanthem induced by aminopenicillins, anaphylaxis by cephalosporins

Table 2 Results of β-lactam-specific serum IgE, skin and challenge testing

	Serum IgE	Prick	Intradermal	Patch	Challenge	Cases (n)
Immediate-type hypersensitivity (n = 70)	+	n.d	n.d	n.a	n.d	7
	–	+	n.d		n.d	6
	–	+	+		n.d	18
	–	–	+		n.d	34
	–	–	–		+	2
	–	–	–		Refused	3
Delayed-type hypersensitivity (n = 135)	n.a.	+	+	–	n.d	6
		+	+	n.d	n.d	8
		+	+	+	n.d	54
		+	n.d	–	n.d	1
		–	+	–	n.d	33
		–	+	+	n.d	11
		–	+	n.d	n.d	3
		–	–	–	+	17
		–	–	–	Refused	2

+ , Positive result; –, negative result; n.a., not applicable; n.d., not done. The criteria defining positive serum IgE, positive prick, positive intradermal, and positive patch testing are described in the Sect ."Methods"

ISSN: 1710-1492