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Table 1 2010 World Allergy Organization (WAO) subcutaneous immunotherapy systemic reaction grading system

From: A single centre retrospective study of systemic reactions to subcutaneous immunotherapy

WAO systemic reaction grade

Reaction characteristics

1

Symptoms from one organ system, excluding asthma, gastrointestinal symptoms or cardiovascular symptoms

2

Asthma, gastrointestinal symptoms or cardiovascular symptoms

3

Patients with symptoms from multiple organ systems, or throat tightness/discomfort suggestive of upper airway edema

4

Hypotension (systolic blood pressure of less than 90 mmHg or less than 30% of baseline) or respiratory failure

5

Death

  1. mmHg millimeter of mercury