Table 3 Summary of patients with grade 4 reactions
From: A single centre retrospective study of systemic reactions to subcutaneous immunotherapy
Age—yr, gender | Reaction year, season | Asthma | Food allergies | SCIT dose | New serum | SCIT content | Reaction onset and symptom description | Treatment |
|---|---|---|---|---|---|---|---|---|
53, male | 2012, winter | Yes | None | Vial 4, 0.25 ml | No | Grass, Ragweed, Trees | Few minutes; flushing, throat tightness, feeling unwell, systolic blood pressure 70 mmHg | Epinephrine 0.5 ml IM then 0.3 ml IM, salbutamol and normal saline. Patient was transferred to the hospital. |
16, male | 2013, autumn | Yes | Peanut and tree nuts | Vial 4, 0.25 ml | Yes | Dust mites, Ragweed, Trees, Mold, Cat | 30 min; shortness of breath, urticaria, flushing, throat tightness, nausea, swelling of the eyes, chest tightness, blood pressure 49/29 upon standing in the hospital | Epinephrine 0.5 ml IM in clinic followed by two injections of epinephrine 0.3 ml IM in the hospital, salbutamol, prednisone, antihistamines and normal saline. Patient was transferred to the hospital |
35, male | 2016, winter | No | None | Vial 4, 0.10 ml | Yes | Dust mites, Grass, Ragweed, Trees, Cat | Immediate; flushing, feeling unwell, lightheadedness, blood pressure 65/40 mmHg after epinephrine was given | Epinephrine 0.5 ml IM then 0.3 ml IM and normal saline. Patient was transferred to the hospital |