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Table 2 Crude and adjusted hazard ratios (95% confidence interval) of asthma for otitis media (≥ 1 time) according to age and sex

From: Bidirectional association between asthma and otitis media in children

Characteristics HRs for otitis media
Crudea P-value Adjusteda,b P-value
Total participants (n = 29,330)
 Asthma 1.51 (1.45–1.57)  < 0.001* 1.46 (1.40–1.52)  < 0.001*
 Control I 1.00   1.00  
Age 5–9 years old (n = 21,674)
 Asthma 1.50 (1.45–1.57)  < 0.001* 1.47 (1.40–1.53)  < 0.001*
 Control I 1.00   1.00  
Age 10–14 years old (n = 7,656)
 Asthma 1.49 (1.35–1.63)  < 0.001* 1.42 (1.29–1.56)  < 0.001*
 Control I 1.00   1.00  
Males (n = 16,232)
 Asthma 1.44 (1.37–1.52)  < 0.001* 1.40 (1.33–1.48)  < 0.001*
 Control I 1.00   1.00  
Females (n = 13,098)
 Asthma 1.58 (1.50–1.68)  < 0.001* 1.53 (1.45–1.62)  < 0.001*
 Control I 1.00   1.00  
  1. *Cox-proportional hazard regression model, Significance at P < 0.05
  2. aStratified model for age, income, and region of residence
  3. bAdjusted model for atopic dermatitis and chronic sinusitis