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Table 4 Crude and adjusted hazard ratios (95% confidence interval) of otitis media (≥ 1 time) for asthma according to age and sex

From: Bidirectional association between asthma and otitis media in children

Characteristics HRs for asthma
Crudea P-value Adjustedab P-value
Total participants (n = 540,86)
Otitis media 1.49 (1.42–1.56)  < 0.001* 1.43 (1.36–1.50)  < 0.001*
Control II 1.00   1.00  
Age 5–9 years old (n = 36,048)
Otitis media 1.51 (1.43–1.59)  < 0.001* 1.45 (1.38–1.53)  < 0.001*
Control II 1.00   1.00  
Age 10–14 years old (n = 18,038)
Otitis media 1.41 (1.27–1.56)  < 0.001* 1.34 (1.20–1.49)  < 0.001*
Control II 1.00   1.00  
Males (n = 28,582)
Otitis media 1.47 (1.39–1.57)  < 0.001* 1.42 (1.33–1.51)  < 0.001*
Control II 1.00   1.00  
Females (n = 25,504)
Otitis media 1.50 (1.40–1.61)  < 0.001* 1.44 (1.35–1.55)  < 0.001*
Control II 1.00   1.00  
  1. *Cox-proportional hazard regression model, Significance at P < 0.05
  2. aStratified model for age, sex, income, and region of residence
  3. bAdjusted model for atopic dermatitis and chronic sinusitis