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Table 4 Crude and adjusted hazard ratios (95% confidence interval) of otitis media (≥ 1 time) for asthma according to age and sex

From: Bidirectional association between asthma and otitis media in children

Characteristics

HRs for asthma

Crudea

P-value

Adjustedab

P-value

Total participants (n = 540,86)

Otitis media

1.49 (1.42–1.56)

 < 0.001*

1.43 (1.36–1.50)

 < 0.001*

Control II

1.00

 

1.00

 

Age 5–9 years old (n = 36,048)

Otitis media

1.51 (1.43–1.59)

 < 0.001*

1.45 (1.38–1.53)

 < 0.001*

Control II

1.00

 

1.00

 

Age 10–14 years old (n = 18,038)

Otitis media

1.41 (1.27–1.56)

 < 0.001*

1.34 (1.20–1.49)

 < 0.001*

Control II

1.00

 

1.00

 

Males (n = 28,582)

Otitis media

1.47 (1.39–1.57)

 < 0.001*

1.42 (1.33–1.51)

 < 0.001*

Control II

1.00

 

1.00

 

Females (n = 25,504)

Otitis media

1.50 (1.40–1.61)

 < 0.001*

1.44 (1.35–1.55)

 < 0.001*

Control II

1.00

 

1.00

 
  1. *Cox-proportional hazard regression model, Significance at P < 0.05
  2. aStratified model for age, sex, income, and region of residence
  3. bAdjusted model for atopic dermatitis and chronic sinusitis