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Fig. 3 | Allergy, Asthma & Clinical Immunology

Fig. 3

From: Catechin synergistically potentiates mast cell-stabilizing property of caffeine

Fig. 3

Effects of low concentrations of catechin on caffeine-induced inhibition of mast cell degranulation. A Differential-interference contrast (DIC) microscopic images were taken after exocytosis was externally induced by compound 48/80 in mast cells incubated in the external solutions containing no substances (a), 10 mM caffeine alone (b), 10 mM caffeine in the presence of 1 mM catechin (c) and 10 mM caffeine in the presence of 2.5 mM catechin (d). B After exocytosis was induced in mast cells incubated in the external solutions containing no substances, 10 mM caffeine alone, 10 mM caffeine in the presence of 1 or 2.5 mM catechin, the numbers of degranulating mast cells were expressed as percentages of the total mast cell numbers in selected bright fields. #p < 0.05 vs. incubation in the external solution alone. *p < 0.05 vs. incubation in the external solution containing 10 mM caffeine alone. Values are means ± SD. Differences were analyzed by ANOVA followed by Tukey’s test

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