Long-term efficacy and safety of subcutaneous C1-inhibitor in women with hereditary angioedema: subgroup analysis from an open-label extension of a phase 3 trial

Table 3 Attack frequency, rescue medication use, and attack severity in the female study population with HAE-C1INH

	All female subjects (n = 76)	Female subjects of childbearing age (n = 42)	Overall study population (N = 126)¹⁸
Number of attacks/month
Mean (SD)	0.50 (0.86)	0.55 (0.88)	0.45 (0.80)
Median (range)	0.10 (0.0–4.0)	0.16 (0.0–4.0)	0.09 (0.0–4.0)
Rescue medication use/month
Mean (SD)	0.33 (0.78)	0.30 (0.76)	0.29 (0.70)
Median (range)	0.0 (0.0–4.5)	0.0 (0.0–4.5)	0.0 (0.0–4.5)
Average severity of attacks^a
Mean (SD)	1.85 (0.44)	1.89 (0.33)	1.69 (0.56)
Median (range)	2.00 (1.0–3.0)	2.00 (1.0–2.5)	1.64 (1.0–3.0)

ISSN: 1710-1492