Table 4 C1-INH (SC) exposure and pregnancy outcomes in subjects with HAE-C1INH who became pregnant during treatment in the OLE
Subject | Age (y) | C1-INH (SC) dose | Total exposure in the OLE | Exposure after last menstruation | Delivery gestation time | Pregnancy outcome |
|---|---|---|---|---|---|---|
1 | 19 | 60 IU/kg | 25.3 weeks (42 doses) | 8 weeks (15 doses) | Caesarean section at 39 weeks | Healthy baby 3.3 kg |
2 | 27 | 60 IU/kg | 43.1 weeks (87 doses) | 5 weeks (10 doses) | Normal forceps at 40 weeks + 5 days | Healthy baby 3.7 kg |
3 | 32 | 40 IU/kg | 35.3 weeks (59 doses) | 5 weeks (10 doses) | Caesarean section at 39 weeks + 3 days | Healthy baby 2.9 kg |
4 | 29 | 60 IU/kg | 27.9 weeks (55 doses) | 4 weeks (9 doses) | Caesarean section at 36 weeks + 6 days | Healthy baby 2.4 kg |