Skip to main content

Table 2 Mannitol compared to methacholine deep inhalation methods and results

From: Comparison of methacholine and mannitol challenges: importance of method of methacholine inhalation

 MCH methodDefinition of positive MCHAsthmaAsthmaNon AsthmaNon Asthma
MCH +veMCH totalMAN +veMAN totalMCH +veMCH totalMAN +veMAN total
1DeVilbiss 40PD20 ≤ 7.8 μmola25252525    
2Nebicheck DosimeterPD20 ≤ 8.0 μmola    1616116
3Mefar dosimeterPD20 ≤ 2 mga–10.2 μmol9111213786386
4Nebicheck DosimeterPD20 ≤ 8.0 μmola43534353    
5ATS DosimeterPC20 ≤ 16 mg/mL1222401322403413536135
6Mefar dosimeterbPD20 ≤ 2 mga–10.2 μmol22482248    
7Spira dosimeterPD20 ≤ 8.0 μmola184217421519314193
8Spira dosimeterPD20 ≤ 8.0 μmola35513051371873187
9Spira dosimeterPC20 ≤ 16 mg/mL9111011017017
10Mefar dosimeterPC20 ≤ 8 mg/mL7412376123    
11Chai dosimeterPC20 ≤ 16 mg/mL22502450154454
12Jaeger dosimeterPD20 ≤ 7.8 μmola791224612232681168
13Spira dosimeterPC20 ≤ 16 mg/mL90134100134    
 Total
%
 548
60.2%
910537
58.9%
912142
18.8%
75672
9.5%
756
 Exclude studies 1, 2 and 9
Total
%
 514
58.8%
874502
57.3%
876126
17.4%
72371
9.8%
723
  1. aPD20 Calculated cumulatively
  2. bPD20 and PD15 calculated manually form response-dose ratio slope graphs