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Table 3 Mannitol compared to methacholine tidal breathing studies

From: Comparison of methacholine and mannitol challenges: importance of method of methacholine inhalation

 

Reference

n

Asthma definition

n

Non asthma definition

Author

Ref #

1

Subbarao et al.

[16]

25

Asthmatic children with positive methacholine test

10

Non asthmatic methacholine negative

2

Koskelka et al.

[17]

37

Mild corticosteroid naïve asthmatics

NB: Histamine

10

Non asthmatic controls

3

Sue-Chu et al.

[18]

10

MD-Dx asthma from 58 cross country skiers

48

Non asthmatic cross country skiers

4

Andregnette et al.

[20]

30

Current asthmatic children

0

 

5

Aronsson et al.

[19]

34

Asthmatics

18

Non asthmatic controls

6

Lemiere et al.

[21]

30

Occupational asthmatics

0

 

7

Andregnette et al.

[22]

23

Asthmatic children with EIB symptoms

0

 

8

Toennesen et al.

[23]

18

MD-Dx asthma from 57 elite athletes

39

Non asthmatic Elite athletes

9

Porpodis et al.

[24]

67

From 88 subjects with asthma-like symptoms

21

Symptoms but no asthma

10

Gutierrez et al.

[25]

156

Asthmatic children

38

Non asthmatic controls

11

Cockcroft et al.

[26,27,28]

26

Mild asthma no ICS

0

 

12

Blais et al.

[29]

20

Mild asthma no ICS

0

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