From: Comparison of methacholine and mannitol challenges: importance of method of methacholine inhalation
 | Reference | n | Asthma definition | n | Non asthma definition | |
---|---|---|---|---|---|---|
Author | Ref # | |||||
1 | Subbarao et al. | [16] | 25 | Asthmatic children with positive methacholine test | 10 | Non asthmatic methacholine negative |
2 | Koskelka et al. | [17] | 37 | Mild corticosteroid naïve asthmatics NB: Histamine | 10 | Non asthmatic controls |
3 | Sue-Chu et al. | [18] | 10 | MD-Dx asthma from 58 cross country skiers | 48 | Non asthmatic cross country skiers |
4 | Andregnette et al. | [20] | 30 | Current asthmatic children | 0 | Â |
5 | Aronsson et al. | [19] | 34 | Asthmatics | 18 | Non asthmatic controls |
6 | Lemiere et al. | [21] | 30 | Occupational asthmatics | 0 | Â |
7 | Andregnette et al. | [22] | 23 | Asthmatic children with EIB symptoms | 0 | Â |
8 | Toennesen et al. | [23] | 18 | MD-Dx asthma from 57 elite athletes | 39 | Non asthmatic Elite athletes |
9 | Porpodis et al. | [24] | 67 | From 88 subjects with asthma-like symptoms | 21 | Symptoms but no asthma |
10 | Gutierrez et al. | [25] | 156 | Asthmatic children | 38 | Non asthmatic controls |
11 | Cockcroft et al. | 26 | Mild asthma no ICS | 0 | Â | |
12 | Blais et al. | [29] | 20 | Mild asthma no ICS | 0 | Â |