From: Long-term outcomes of 0.1% tacrolimus eye drops in eyes with severe allergic conjunctival diseases
Time | Number of patient (case) | Symptom Score (point) | SD | 95% CI | Change from baseline (point) | SD | 95% CI | P value* | ||
---|---|---|---|---|---|---|---|---|---|---|
0 M (BL) | 12 | 14.3 | 1.09 | 12.1 | 16.6 | |||||
0.5 M | 12 | 7.33 | 1.09 | 5.06 | 9.61 | 7.00 | 0.80 | 5.43 | 8.57 | < .001 |
1 M | 12 | 7.21 | 1.09 | 4.93 | 9.48 | 7.13 | 0.80 | 5.56 | 8.69 | < .001 |
2 M | 12 | 7.63 | 1.09 | 5.35 | 9.90 | 6.71 | 0.80 | 5.14 | 8.27 | < .001 |
3 M | 12 | 7.08 | 1.09 | 4.81 | 9.36 | 7.25 | 0.80 | 5.68 | 8.82 | < .001 |
6 M | 12 | 5.71 | 1.09 | 3.43 | 7.98 | 8.63 | 0.80 | 7.06 | 10.2 | < .001 |
1Y | 12 | 5.54 | 1.09 | 3.27 | 7.82 | 8.79 | 0.80 | 7.23 | 10.4 | < .001 |
2Y | 12 | 7.17 | 1.09 | 4.89 | 9.44 | 7.17 | 0.80 | 5.60 | 8.73 | < .001 |
3Y | 12 | 6.71 | 1.09 | 4.43 | 8.98 | 7.63 | 0.80 | 6.06 | 9.19 | < .001 |
4Y | 12 | 7.00 | 1.09 | 4.73 | 9.27 | 7.33 | 0.80 | 5.77 | 8.90 | < .001 |
5Y | 12 | 5.33 | 1.09 | 3.06 | 7.61 | 9.00 | 0.80 | 7.43 | 10.6 | < .001 |
6Y | 12 | 5.25 | 1.09 | 2.98 | 7.52 | 9.08 | 0.80 | 7.52 | 10.6 | < .001 |
7Y | 6 | 5.59 | 1.24 | 3.07 | 8.11 | 8.75 | 0.99 | 6.80 | 10.7 | < .001 |
8Y | 5 | 4.29 | 1.29 | 1.68 | 6.91 | 10.0 | 1.05 | 7.97 | 12.1 | < .001 |
9Y | 5 | 4.39 | 1.29 | 1.78 | 7.01 | 9.94 | 1.05 | 7.87 | 12.0 | < .001 |
10Y | 5 | 3.49 | 1.29 | 0.88 | 6.11 | 10.8 | 1.05 | 8.77 | 12.9 | < .001 |