Table 1 Phenotype of T cells in blister fluid (BF) and peripheral blood (PB)
Total CD3+ | CD4+CD8− | CD4−CD8+ | CD4 +CD8+ | |||||
|---|---|---|---|---|---|---|---|---|
BF | PB | BF | PB | BF | PB | BF | PB | |
TRM cell marker | ||||||||
CD69+ | 68.4 | 3.30 | 67.4 | 0.52 | 66.9 | 5.91 | 68.2 | 1.26 |
CD69+CD103 + | 6.23 | NA | 3.56 | NA | 8.33 | NA | 6.91 | NA |
MAIT cell marker | ||||||||
MR1+ (5-OP-RU) | 1.25 | 2.09 | 0.50 | 0.28 | 3.16 | 4.36 | 0.34 | 0.46 |
NKT cell marker | ||||||||
CD16/56+ | 64.6 | 24.4 | 1.41 | 1.14 | 67.2 | 36.3 | 87.9 | 86.1 |
Memory marker | ||||||||
CD45RA+ | 11.5 | 68.2 | 0.67 | 62.7 | 20.7 | 78.4 | 10.6 | 61.1 |
Naive (CD45RA+CCR7 +) | NA | 41.3 | NA | 62.4 | NA | 32.8 | NA | 4.06 |
TEMRA (CD45RA+CCR7− | NA | 26.9 | NA | 0.27 | NA | 45.6 | NA | 57.0 |
TCM (CD45RA−CCR7+) | NA | 10.0 | NA | 20.7 | NA | 1.08 | NA | 0.55 |
TEM (CD45RA−CCR7−) | NA | 21.8 | NA | 16.6 | NA | 20.6 | NA | 38.4 |
Activation/differentiation marker | ||||||||
CD69+ | 68.4 | 3.30 | 67.4 | 0.52 | 66.9 | 5.91 | 68.2 | 1.26 |
HLA-DR+ | 37.3 | 19.0 | 25.4 | 4.76 | 24.6 | 20.3 | 52.6 | 65.7 |
CD11ahigh | 81.5 | 42.7 | 46.0 | 13.2 | 84.3 | 61.3 | 94.7 | 95.6 |
CD57+ | 33.1 | 25.9 | 3.77 | 2.46 | 33.9 | 38.6 | 48.0 | 77.3 |
CD28+ | 32.1 | 69.2 | 99.2 | 99.0 | 34.1 | 53.8 | 0.70 | 5.33 |