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Table 1 Summary of demographic findings and timing of C1-INH administration, dose, and time to angioedema resolution (marked by time to extubation)

From: Effectiveness of C1-INH therapy in angiotensin converting enzyme inhibitor induced angioedema

Case

Age

Sex

ACEi

Diabetes

NSAIDs

Time from onset of symptoms to drug administration

Dose of Berinert

Time to Resolution of symptoms

1

80

F

Ramipril

No

No

6.5 h

1500 IU

12.5 h

2

57

F

Ramipril

No

No

22 h

1500 IU

12 h

3

67

F

Perindopril

Yes

Yes

9.5 h

1000 IU

500 IU

35 h

4

70

M

Perindopril

Yes

Yes

1 h

1500 IU

32.5 h

5

77

M

Quinapril

Yes

Yes

7 h

1500 IU

1000 IU

72 h

6

62

F

Lisinopril

No

No

5 h

Recurrence of symptoms 24 h later→ 4 h

1500 IU

1000 IU

14 h

26 h

7

64

F

Enalapril

No

No

25 h

1000 IU

13 h

8

67

F

Ramipril

Yes

No

10 h

1500 IU

No response within 4 h → received 30 mg Icabitant → 22 h

9

70

M

Enalapril

Yes

No

11 h

1500 IU

14 h