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Table 5 ADAM33 promoter methylation levels between the AR and control groups stratified by environmental risk factors

From: Interaction between early-life pet exposure and methylation pattern of ADAM33 on allergic rhinitis among children aged 3–6 years in China

Variable

AR

Mean ADAM33 promoter methylation levels

Control

Mean ADAM33 promoter methylation levels

N

130

 

154

 

Maternal allergic history

    

 Yes

75 (57.69)

0.2018 ± 0.008417

70 (45.45)

0.2073 ± 0.01042

 No

55 (42.31)

0.2029 ± 0.007894

84 (54.55)

0.2081 ± 0.01130

P-value

 

0.346

 

0.897

Exposed to pet

    

 Yes

49 (37.69)

0.2012 ± 0.008346

40 (25.97)

0.2098 ± 0.01172

 No

81 (62.31)

0.2044 ± 0.007349

114 (74.03)

0.2062 ± 0.01015

P-value

 

0.009

 

0.290

  1. Values are presented as means ± SD or numbers. A comparison between AR and control groups by Mann–Whitney U test. Significant results are in italics