Fig. 5

Mean Total Rhinoconjunctivitis Symptom Score (TRSS). All of the participants’ ranked symptoms were tallied as the TRSS (max 24). A steady increase in symptoms were observed for all allergic participants, peaking at 3 h, though those exposed to a higher HDM target achieved a mean peak TRSS of 14.08 ± 1.30 compared to 9.16 ± 1.32 for those exposed to a moderate HDM target. Comparisons between modest target allergics and non-allergics are represented by “†”, high target allergics and non-allergics by “‡” and modest and high target allergics by “*”. †/‡/* = p < 0.05, ††/‡‡/** = p < 0.01, †††/‡‡‡/*** = p < 0.001, ††††/‡‡‡‡/**** = p < 0.0001