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Table 3 The scores of observation indexes before and after treatment of chronic urticaria in the experiment group and the placebo group (means ± sd)

From: Adjunct therapy with probiotics for chronic urticaria in children: randomised placebo-controlled trial

Group

Before treatment

After treatment

W1 (day 7)

W2 (day 14)

W4 (day 28)

Pruritus

 Experiment

2.19 ± 0.66

0.80 ± 0.85

0.53 ± 0.72

0.39 ± 0.67

 Placebos

2.19 ± 0.68

1.00 ± 0.92

0.66 ± 0.76

0.46 ± 0.77

Number of wheals

 Experiment

2.44 ± 0.63

0.70 ± 0.89

0.42 ± 0.80

0.90 ± 1.01

 Placebos

2.40 ± 0.67

0.84 ± 0.90

0.58 ± 0.09

1.09 ± 1.05

Size of wheals

 Experiment

2.27 ± 0.79

1.01 ± 0.96

0.63 ± 0.82

0.39 ± 0.72#,*

 Placebos

2.39 ± 0.69

1.06 ± 1.01

0.66 ± 0.89

0.52 ± 0.79

Duration of attack

 Experiment

2.05 ± 0.64

0.90 ± 0.99

0.66 ± 0.83

0.42 ± 0.72

 Placebos

2.15 ± 0.73

1.03 ± 1.00

0.83 ± 0.87

0.48 ± 0.77

Attacks per week

 Experiment

7.13 ± 3.06

4.31 ± 3.96

3.01 ± 3.57

1.03 ± 3.96#,**

 Placebos

7.73 ± 5.74

4.91 ± 5.27

3.43 ± 4.26

2.51 ± 4.17

  1. #On Day 7 after beginning treatment, the wheal size score and attacks per week between the experiment group and the placebo group separately were compared by the rank-sum test, and the results were Z = 1.94, p = 0.05 (*) and Z = 2.15, p = 0.02 (**), respectively