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Table 3 The scores of observation indexes before and after treatment of chronic urticaria in the experiment group and the placebo group (means ± sd)

From: Adjunct therapy with probiotics for chronic urticaria in children: randomised placebo-controlled trial

Group Before treatment After treatment
W1 (day 7) W2 (day 14) W4 (day 28)
Pruritus
 Experiment 2.19 ± 0.66 0.80 ± 0.85 0.53 ± 0.72 0.39 ± 0.67
 Placebos 2.19 ± 0.68 1.00 ± 0.92 0.66 ± 0.76 0.46 ± 0.77
Number of wheals
 Experiment 2.44 ± 0.63 0.70 ± 0.89 0.42 ± 0.80 0.90 ± 1.01
 Placebos 2.40 ± 0.67 0.84 ± 0.90 0.58 ± 0.09 1.09 ± 1.05
Size of wheals
 Experiment 2.27 ± 0.79 1.01 ± 0.96 0.63 ± 0.82 0.39 ± 0.72#,*
 Placebos 2.39 ± 0.69 1.06 ± 1.01 0.66 ± 0.89 0.52 ± 0.79
Duration of attack
 Experiment 2.05 ± 0.64 0.90 ± 0.99 0.66 ± 0.83 0.42 ± 0.72
 Placebos 2.15 ± 0.73 1.03 ± 1.00 0.83 ± 0.87 0.48 ± 0.77
Attacks per week
 Experiment 7.13 ± 3.06 4.31 ± 3.96 3.01 ± 3.57 1.03 ± 3.96#,**
 Placebos 7.73 ± 5.74 4.91 ± 5.27 3.43 ± 4.26 2.51 ± 4.17
  1. #On Day 7 after beginning treatment, the wheal size score and attacks per week between the experiment group and the placebo group separately were compared by the rank-sum test, and the results were Z = 1.94, p = 0.05 (*) and Z = 2.15, p = 0.02 (**), respectively