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Table 4 Proportion(%) of CGD with high or low Immune parameters in Malaysian patients with CGD

From: Clinical and demographic pattern of chronic granulomatous disease (CGD) from a multicenter perspective: Malaysia’s experience over 26 years

Immune parameters

High levels*

Normal levels

Low levels**

N (%)

N (%)

N (%)

Lymphocyte subsets

CD3+/T cells (N = 15)

7 (46.6%)

7 (46.6)

1 (6.7%)

CD4+/Th cells (N = 11)

3 (27.3%

4 (36.4)

4. (36.4%)

CD8 /Tc cells (N = 11)

4 (36.4%)

5 (45.5)

2 (18.2)

B cell (N = 15)

3 (20 %)

8 (53.3 %)

4 (26.6% )

Serum immunoglobulins

IgG (N = 15

11 (73)

3 (20)

1 (6)

IgA (N = 14)

12 (86)

2 (14.2)

0

IgM (N = 15)

8 (53)

7 (47)

0

  1. *Above normal range for age matched healthy children
  2. **Below normal range for age matched healthy children
  3. Normal & high level IgG. 14/15 (93.3%) CD3+ cells 14/15(93.3%)
  4. IgA. 14/14. (100%) CD4+ cells 7/11 (63.6%)
  5. IgM. 15/15. (100%) CD8+ cells 9/11 ( 81.8%)