Table 1 Differentially expressed genes associated with inflammatory response; including; regulation of neutrophil migration and chemotaxis, macrophage differentiation and chemotaxis, mast cell activation, degranulation and mast cells mediated immunity, phagocytosis, and cell response for lipoteichonic acid in hNECs exposed to 25 μg/ml O3BC + 200 μg/ml pollen vs control hNECs
Biological function | Related Gene | Log2FC | q-value | Biological function | Related Gene | Log2FC | q-value |
|---|---|---|---|---|---|---|---|
Regulation of neutrophil degranulation, migration and chemotaxis | CCL20 | 8.81 | 5.01E−37 |  | TLR2 | 1.27 | 3.71E−21 |
ITGAM | 7.72 | 8.65E−22 | Regulation of phaocytosis | ITGAM | 7.72 | 8.65E−22 | |
CXCL8 | 7.59 | 3.29E−68 | DOCK2 | 6.53 | 5.20E−17 | ||
IL1B | 6.22 | 2.87E−56 | IL1B | 6.22 | 2.87E−56 | ||
S100A9 | 5.99 | 7.24E−06 | CD14 | 5.86 | 3.80E−14 | ||
CXCL5 | 4.76 | 2.44E−06 | PTPRC | 5.55 | 9.34E−07 | ||
IL1R1 | 3.63 | 7.47E−09 | CD36 | 3.72 | 1.71E−10 | ||
CSF3R | 3.15 | 1.04E−05 | SLC11A1 | 3.12 | 2.54E−14 | ||
RAC2 | 3.05 | 2.40E−16 | RAC2 | 3.05 | 2.40E−16 | ||
CXCL3 | 2.01 | 1.51E−09 | MERTK | 2.82 | 1.21E−07 | ||
IL1A | 1.14 | 1.01E−07 | Regulation of mast cells degranulation, activation and mast cells mediated immunity | VAV1 | 4.76 | 2.44E−06 | |
Macrophage differentiation, chemotaxis | HCLS1 | 7.29 | 7.19E−19 | FGR | 4.43 | 1.89E−10 | |
MMP9 | 6.06 | 1.24E−48 | FES | 3.40 | 0.000367 | ||
LPL | 5.59 | 5.24E−07 | RAC2 | 3.05 | 2.40E−16 | ||
CSF1 | 4.23 | 4.08E−15 | MILR1 | 1.87 | 0.01 | ||
CD36 | 3.72 | 1.71E−10 | LAT2 | 1.26 | 2.48E−07 | ||
CSFR1 | 3.37 | 7.25E−18 | FCER1G | 1.21 | 8.12E−17 |