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Table 2 upstream regulators associated with inflammatory response in hNECs exposed to 25 μg/ml O3BC+ 200 μg/ml pollen vs control hNECs

From: Assessment of changes in genetic transcriptome in nasal epithelial cells exposed to ozone-aged black carbon and pollen allergen by high-throughput transcriptomics

Upstream regulator Expr Log Ratio Activation z-score p-value of overlap
IL1B 6.00 4.41 1.13E−14
CSF1 4.01 3.68 1.87E−12
CCL2 3.93 1.37 4.51E−10
TLR2 6.75 3.39 6.33E−08
LPL 3.88 0.71 1.67E−07
IGF8 6.47 2.01 6.48E−07
SPP1 10.13 2.74 1.101E−06
CXCL8 5.57 2.29 9.69E−08
FCER1G 3.21 2.11 0.0000018
IL1RN 7.89 − 2.61 3.07E−08