Expression levels of plasma exosomal miR-124, miR-125b, miR-133b, miR-130a and miR-125b-1-3p in severe asthma patients and normal individuals with emphasis on inflammatory factors

Table 2 Relative expression (fold change) of different microRNAs in exosomes isolated from sera samples of asthma patients and controls

miRNA	Relative expression	P-value	overall expression
miR 124	0.19 ± 0.09	< 0.0001*	DOWN
miR 125b	4.17 ± 2.92	< 0.0001*	UP
miR 133b	0.20 ± 0.08	< 0.0001*	DOWN
miR 130a	0.17 ± 0.14	< 0.0001*	DOWN
miR 125b-3p	0.76 ± 0.54	0.156	No change

Purification and characterization of plasma exosomes have been described in the ‘Methods’ section. Fold change is presented as Mean ± SD. *p < 0.0001 is considered as significant. The overall expression shows differences in expression between the asthma patients and controls

ISSN: 1710-1492