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Table 3 Summary of Identified Risk Factors for Patients with Systemic Reactions to SCIT

From: Systemic reactions to subcutaneous allergen immunotherapy: real-world cause and effect modelling

Risk factor

Number of patients

1. First injection from a new serum vial

4

2. Seasonal exacerbation of allergic disease

4

3. History of previous systemic reactions to SCIT

3

4. Sub-optimally controlled asthma

2

5. Omission of pre-medication

1

6. Exercise 1 h prior to injection

1

7. ACE-Inhibitor and NSAID usage coinciding with injection

1

8. Intramuscular administration

1

  1. ACE Angiotensin converting enzyme, NSAID Nonsteroidal anti-inflammatory drug, SCIT Subcutaneous immunotherapy