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Table 2 Comparison of laboratory indexes between early-onset group and late-onset group

From: Increased levels of serum IL-17 and induced sputum neutrophil percentage are associated with severe early-onset asthma in adults

 

All (n = 64)

Early-onset group (n = 32)

Late-onset group (n = 32)

t/Z

P

Peripheral blood

 WBC, (109/L), Mean ± SD

8.00 ± 2.29

8.25 ± 2.13

7.75 ± 2.46

0.860

0.393

 Neu, (109/L), Mean ± SD

5.30 ± 2.38

5.80 ± 2.17

5.02 ± 2.57

0.951

0.345

 Eos%, (%), Median (Q1, Q3)

2.2 (0.2, 7.5)

1.0 (0.2, 7.3)

3.7 (0.2, 7.5)

1.717

0.241

 Eos, (109/L), Median (Q1, Q3)

0.22 (0.02, 0.53)

0.07 (0.01, 0.53)

0.28 (0.03, 0.53)

1.124

0.261

 Neu/Eos, Median (Q1, Q3)

15.48 (6.79, 82.25)

24.92 (6.94, 131.91)

12.19 (6.05, 54.24)

0.737

0.461

 IL-5, (ng/L), Median (Q1, Q3)

87.28 (35.79, 108.2)

89.54 (37.94, 104.34)

87.16 (29.49, 111.68)

0.156

0.876

 IL-17, (ng/L), Median (Q1, Q3)

51.10 (40.25,81.98)

52.96 (47.99,105.50)

44.75 (20.81, 54.99)

2.400

0.016*

 HVEM, (pg/L), Median (Q1, Q3)

87.23 (54.19, 109.2)

84.18 (57.21, 95.01)

94.75 (43.81, 115.69)

0.782

0.434

Induced sputum

 Neu%, (%), Mean ± SD

60.98 ± 28.68

72.04 ± 26.90

53.61 ± 27.89

2.202

0.033*

 Eos%, (%), Median (Q1, Q3)

12.45 (1.40, 32.35)

3.8 (1.4, 14.4)

13.4 (2.8, 39.2)

1.490

0.136

 Neu%/Eos%, Median (Q1, Q3)

5.99 (1.14, 48.40)

12.60 (3.23, 63.74)

2.62 (1.00, 23.25)

1.219

0.223

FeNO, (ppb), Median (Q1, Q3)

27.0 (16.0, 49.5)

22.5 (16.0, 47.3)

32.5 (16.0, 50.3)

0.559

0.576

  1. WBC: white blood cell; SD: standard deviation; Neu: neutrophil; Eos: eosinophil; Q1: quartile 1; Q3: quartile 3; SB: standard bicarbonate; IL: interleukin; HVEM: herpes virus entry mediator; FeNO: fractional exhaled nitric oxide; ppb: part per billion
  2. *Represent P < 0.05, suggest statistical significance