Table 5 Interactions between IL13 rs20541, IL13 rs1800925, IL4 rs2243250 and ADRB2 rs1042713 genotypes for CBIgE elevation
From: Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children
Number of risk genotype for the four SNPs a | CBIgE levels | P value † | OR (95%CI) | |
|---|---|---|---|---|
Elevated, n (%) | Normal, n (%) | |||
0 | 31 (13.2) | 110 (16.8) | 1 | |
1 | 92 (39.1) | 265 (40.4) | 3.78 × 10–1 | 1.23 (0.78–1.96) |
2 | 71 (30.2) | 217 (33.1) | 5.42 × 10−1 | 1.16 (0.72–1.88) |
3 | 34 (14.5) | 58 (8.8) | 1.28 × 10–2 | 2.08 (1.16–3.72) |
4 | 7 (3.0) | 6 (0.9) | 2.69 × 10–2 | 4.14 (1.30–13.22) |