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Table 6 Interactions between the nine SNPs and maternal atopy for CBIgE elevation

From: Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children

Gene

SNP

Minor allele

OR(95%CI)

P value*

IL13

rs1800925

T

1.21 (0.86–1.71)

2.81 × 10–1

IL13

rs1295686

A

0.89 (0.67–1.20)

4.53 × 10–1

IL13

rs20541

T

0.91 (0.68–1.22)

5.25 × 10–1

IL4

rs2243250

C

1.41 (1.04–1.91)

2.65 × 10–2

ADRB2

rs1042713

G

0.86 (0.66–1.14)

2.94 × 10–1

FCER1B

rs1441586

C

1.21 (0.91–1.59)

1.91 × 10–1

FCER1B

rs569108

C

1.19 (0.84–1.69)

3.19 × 10–1

IL4RA

rs1805010

A

0.89 (0.68–1.16)

3.77 × 10–1

IL4RA

rs1801275

G

1.23 (0.88–1.72)

2.31 × 10–1

  1. SNP single-nucleotide polymorphism, CBIgE cord blood IgE, OR odds ratio, CI confidence interval
  2. *P Values were tested by multivariate logistic regression, adjusted for other genes, but not for other environmental factors