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Table 1 RegiSCAR Criteria for DRESS Syndrome with our patient’s score calculated in the right most column with a total score of 4 (probable)

From: Liver enzyme elevation and eosinophilia with atorvastatin: a case of probable DRESS without cutaneous symptoms

Scoring Criteria

Score modifier if present

Score modifier if absence

Special score considerations

Scoring for our patient

Fever (≥ 38.5 °C)

0

− 1

Present (0)

Lymphadenopathy (> 1 cm in two sites)

1

0

Absent (0)

Eosinophilia

1 (If > 700 cells/µL)

0

2 (if > 1500 cells/µL)

Highly present (2)

Atypical lymphocytosis (on blood film)

1

0

N/A

Not assessed (0)

Skin rash (> 50% body surface area)

1

0

Absent (0)

Skin Biopsy (if applicable)

1 (if + for DRESS)

− 1 (if negative for DRESS)

Not assessed (0)

Organ involvement

1

0

If more than one organ involvement + 1 score for a total of 2

One organ involvement (1)

Resolution > 15 days

0

− 1

Present (0)

Other causes excluded (3 or more of below negative)

Antinuclear antibody

Blood culture

Serology for viral hepatitis

Chlamydia/mycoplasma

1

0

3 causes ruled out (1)