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Table 3 Diagnostic values of serum 14-3-3β in asthmatic subgroup comparing with normal control group

From: Serum 14-3-3β protein: a new biomarker in asthmatic patients with acute exacerbation in an observational study

 

Acute Exacerbation group

Chronic Persistent group

Serum 14-3-3β (ng/mL)

AUC (95% confidence interval)

0.90 (95% CI 0.85–0.96)

0.60 (95% CI 0.49–0.70)

P

P < 0.001

P > 0.05

Cut-off value

29.70 ng/mL

29.70 ng/mL

Sensitivity (%)

92.6

44.0

Specificity (%)

75.9

75.9

+LR

3.84

1.83

−LR

0.10

0.74

Youden index

0.69

0.22

  1. Bolding indicates statistical significance
  2. AUC: area under the curve; +LR: positive likelihood ratio; −LR: negative likelihood ratio
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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