Fig. 3
From: MiRNA-221-5p suppressed the Th17/Treg ratio in asthma via RORγt/Foxp3 by targeting SOCS1
Over-expression of miRNA-221-5p regulates imbalance of Th17 and Treg Cells in model asthma through RORγt/Foxp3 by Targeting SOCS1. Heat map (A), network signal (B), Network signal analysis (C), 3’UTR region of SOCS1 showed potential alignment with miRNA-221-5p sequence (D), luciferase reporter activity levels (E). Negative, negative mimics group; miR-221-5p, Over-expression of miRNA-221-5p group. **p < 0.01 versus negative mimics group