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Fig. 5 | Allergy, Asthma & Clinical Immunology

Fig. 5

From: MiRNA-221-5p suppressed the Th17/Treg ratio in asthma via RORγt/Foxp3 by targeting SOCS1

Fig. 5

Down-regulation of miRNA-221-5p regulates imbalance of Th17 and Treg Cells in model asthma through RORγt/Foxp3 by Targeting SOCS1. The expression of miRNA-221-5p (A), IL-6 (B), IL-17 (C), IL-21 (D), IL-22 (E), IL-10 (F), IL-35 (G) and TGF-β (H) levels, SOCS1, RORγt and Foxp3 protein expression by statistical analysis (IK) and western blotting analysis (L). Negative, negative mimics group; anti-221-5p, down-regulation of miRNA-221-5p group. **p < 0.01 versus negative mimics group

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