Fig. 7
From: MiRNA-221-5p suppressed the Th17/Treg ratio in asthma via RORγt/Foxp3 by targeting SOCS1
The inhibition of RORγt reduced the effects of anti-miRNA-221-5p on Th17/Treg Ratio in asthma. RORγt and Foxp3 protein expression by statistical analysis (A and B) and western blotting analysis (C), IL-6 (D), IL-17 (E), IL-21 (F), IL-22 (G), IL-10 (H), IL-35 (I) and TGF-β (J) levels. Negative, negative mimics group; anti-221-5p, down-regulation of miRNA-221-5p group; si-RORγt, si-RORγt and down-regulation of miRNA-221-5p group. **p < 0.01 versus negative mimics group, ##p < 0.01 versus down-regulation of miRNA-221-5p group.