Stratification
|
Number of studies
|
I2
|
Model
|
OR (95% CI)
|
---|
Overall
|
12
|
87.80%
|
Random
|
1.07 (0.94–1.21)
|
Study design
|
Case–control
|
1
|
–
|
Random
|
0.87 (0.56–1.35)
|
Cohort
|
5
|
76.60%
|
Random
|
1.05 (0.86–1.29)
|
Cross-sectional
|
6
|
88.80%
|
Random
|
1.08 (0.91–1.29)
|
Study site
|
Europe
|
5
|
91.20%
|
Random
|
0.94 (0.69–1.28)
|
North America
|
4
|
65.10%
|
Random
|
1.06 (0.88–1.27)
|
Asia
|
3
|
0%
|
Random
|
1.16 (1.08–1.25)*
|
Sample size
|
< 5000
|
3
|
30.7%
|
Random
|
0.80 (0.54–1.18)
|
5000–10,000
|
1
|
–
|
Random
|
0.32 (0.20–0.52)*
|
10,000–50,000
|
3
|
43.20%
|
Random
|
1.10 (0.98–1.25)
|
50,000–100,000
|
3
|
0%
|
Random
|
1.15 (1.07–1.24)*
|
> 100,000
|
2
|
0%
|
Random
|
1.41 (1.33–1.50)*
|
Asthma definition
|
Questionnaire
|
5
|
87.50%
|
Random
|
0.72 (0.43–1.20)
|
Medical record
|
7
|
88.70%
|
Random
|
1.19 (1.04–1.35)*
|
- SGA small for gestational age
- *P < 0.05