Stratification | Number of studies | I2 | Model | OR (95% CI) | |
---|---|---|---|---|---|
Overall | 12 | 87.80% | Random | 1.07 (0.94–1.21) | |
Study design | Case–control | 1 | – | Random | 0.87 (0.56–1.35) |
Cohort | 5 | 76.60% | Random | 1.05 (0.86–1.29) | |
Cross-sectional | 6 | 88.80% | Random | 1.08 (0.91–1.29) | |
Study site | Europe | 5 | 91.20% | Random | 0.94 (0.69–1.28) |
North America | 4 | 65.10% | Random | 1.06 (0.88–1.27) | |
Asia | 3 | 0% | Random | 1.16 (1.08–1.25)* | |
Sample size | < 5000 | 3 | 30.7% | Random | 0.80 (0.54–1.18) |
5000–10,000 | 1 | – | Random | 0.32 (0.20–0.52)* | |
10,000–50,000 | 3 | 43.20% | Random | 1.10 (0.98–1.25) | |
50,000–100,000 | 3 | 0% | Random | 1.15 (1.07–1.24)* | |
> 100,000 | 2 | 0% | Random | 1.41 (1.33–1.50)* | |
Asthma definition | Questionnaire | 5 | 87.50% | Random | 0.72 (0.43–1.20) |
Medical record | 7 | 88.70% | Random | 1.19 (1.04–1.35)* |