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Table 1 Characteristics of the study and control groups

From: Impact of comorbidities on risk of angioedema without urticaria in elderly patients

  Study group,
n = 242
Control group,
n = 263
ASD
Mean age (range; in years) 68.3 (60–88) 65.9 (60–91) 0.120
Mean BMI (kg/m2) ± SD 24.1 ± 6.4 27.2 ± 5.8 0.151
Female (%) 138 (57) 152 (58) 0.006
Rural area (%) 115 (48) 140 (53) 0.081
Smoker or former smoker (%) 97 (40) 99 (37) 0.012
Comorbidities (%)
One chronic disease 65 (27) 74 (28) 0.181
Two chronic diseases 110 (45) 121 (46) 0.176
 > Two chronic diseases 67 (28) 83 (32)* 0.048
No. of angioedema incidences (%)  
One 54 (22)   
Two to five 161 (67)   
Six or more (recurrent) 27 (11)   
Emergency intervention 48 (20)
Hospitalization due to angioedema 63 (26)   
Mean time of onset in minutes (range) 18 min (2–129)   
Localization
Mouth 179 (74)   
Eye area 104 (43)   
Throat 62 (26)   
Hands or feet 75 (31)   
Respiratory tract 32 (13)   
Digestive tract 29 (12)   
Others 19 (8)   
Symptomatic medications used to treat angioedema (%)  
 Antihistamines 219 (90)   
 Adrenaline 17 (7)   
 Systemic steroids 114 (47)   
 Calcium 176 (73)   
 Montelukast 51 (21)   
 Tranexamic acid 11 (5)   
 Blood plasma 2 (1)   
  1. ASD absolute standardized difference, SD standard deviation, BMI body mass index
  2. *Borderline statistical significance