Table 1 Patient history (data from allergist directed testing): type of hypersensitivity reaction, incriminated β-lactam antibiotic, route of intake or administration, and time interval between the β-lactam-associated reaction and allergy testing in 800 patients with suspected β-lactam hypersensitivity
From: Outcome of a de-labelling algorithm compared with results of penicillin (β-lactam) allergy testing
Immediate reaction (n = 334) | Delayed reaction (n = 421) | Assignment uncertain (n = 45) | |
|---|---|---|---|
Culprit β-lactam antibiotic | |||
Aminopenicillin (amoxicillin or ampicillin) | 111 | 287 | 13 |
Cephalosporin | 144 | 47 | 3 |
Benzyl/phenoxymethyl penicillin | 45 | 55 | 9 |
Other | 4 | 2 | 0 |
Unclear or insufficiently documented | 30 | 30 | 20 |
Route of intake or administration | |||
Oral | 235 | 346 | 40 |
Intravenous | 97 | 75 | 2 |
Intramuscular | 1 | 0 | 1 |
Unclear or not sufficiently documented | 1 | 0 | 2 |
Time interval between β-lactam-associated reaction and allergy testing | |||
≤ 1 year | 214 | 274 | 3 |
> 1–5 years | 31 | 46 | 2 |
> 5–10 years | 13 | 14 | 3 |
> 10 years | 71 | 80 | 30 |
Unclear or insufficiently documented | 5 | 7 | 7 |