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Table 2 Comparison of results of allergy testing and outcome of the de-labelling algorithm

From: Outcome of a de-labelling algorithm compared with results of penicillin (β-lactam) allergy testing

Allergy testing (data from allergist directed testing)

Outcome of de-labelling algorithm (blinded investigator assessment)

Sum

De-labelling

Use alternative antibiotic

β-lactam hypersensitivity excluded

330 (55.5%)

265 (44.5%)

595 (100%)

Allergic β-lactam hypersensitivity proven (any type)

21 (10.2%)

184 (89.8%)

205 (100%)

 Immediate-type (anaphylaxis)

8 (11.4%)

62 (88.6%)

70 (100%)

  Mild

7

19

26

  Moderate

1

26

27

  Severe

0

17

17

 Delayed-type

13 (9.6%)

122 (90.4%)

135 (100%)

  Measles-like (maculopapular) exanthema

11

106

117

  SDRIFE

2

10

12

  FDE

0

3

3

  DRESS

0

3

3

  1. DRESS drug reaction with eosinophilia and systemic symptoms, FDE fixed drug eruption, SDRIFE symmetrical drug related intertriginous and flexural exanthema