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Table 3 Evaluation of genetically based myeloproliferative disorders, malignancies, and primary immune deficiencies

From: Hypereosinophilic syndrome presenting as coagulopathy

JAK2 V617F mutation

Not detected

CALR mutation

Not detected

JAK2 Exon 12 mutation

Not detected

MPL Exon 10 mutation

Not detected

CSF3R Exon 14/17 mutation

Not detected

Hereditary hemochromatosis DNA mutation analysis

No mutations detected

SCFD2, LNX, FIP1L1, CHIC2, PDGFRA/KIT on Chromosome 4q12

No rearrangements detected on interphase fluorescence in situ hybridization (IFISH)

PDGFRB

No rearrangements detected on IFISH

FGFR1

No rearrangements detected on IFISH

BCR/ABL p210 Interpretation

No BCR/ABL b2:a2 (e13:a2) or b3:a2 (e14:a2) transcripts detected

University of Washington Heme Gene Panel (ASXL1, CBL, CSF3R, DNMT3A, EZH2, FBXW7, FGFR1, FLT3, GATA1, GATA2, HRAS, IDH1, IDH2, JAK2, KIT, KMT2A, KRAS, MAP2K1, MPL, MYD88, NOTCH1, NPM1, NRAS, PDGFRA, PHF6, PTEN, RB1, RUNX1, SF3B1, SRSF2, STAG2, STAT3, TET2, TP53, U2AF1, WT1, ZRSR2)

No pathogenic mutations detected