Fig. 1

Mast cell activation [6, 10,11,12]. DAMPs damage-associated molecular patterns, ECP eosinophil cationic proteins, FcεRI high affinity IgE receptor, IgE immunoglobulin E, IgG immunoglobulin G, MRGPRX2 mas-related G-protein coupled receptor X2, MBP major basic protein, PAF platelet activating factor, PAMPs pathogen-associated molecular pattern, SCF stem cell factor, TLR toll-like receptor, TNF-α tumor necrosis factor α, TPO thyroid peroxidase