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Fig. 5 | Allergy, Asthma & Clinical Immunology

Fig. 5

From: Intractable middle ear effusion in EGPA patients might cause permanent hearing loss: a case–control study

Fig. 5

Serial changes in otologic symptoms and use of steroid/anti-IL-5 in 2 EGPA patients with recurrent MEE. (A) Patient A developed MEE while tapering maintenance steroids and (B) Patient B had MEE at the time of EGPA diagnosis. VT insertion/myringotomy and IT injections temporarily improved symptoms but steroid maintenance dosage had to be eventually increased. MEE waxed and waned based on steroid dose, which was better controlled after addition of anti-IL-5, without any events requiring additional steroids. EGPA, eosinophilic granulomatosis with polyangiitis; MEE, middle ear effusion; VT, ventilation tube; IT, intratympanic

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