Sodium chloride | TSPP | |||||
---|---|---|---|---|---|---|
Population size clinical assessment results | ||||||
Pre administration | Post administration | p | Pre administration | Post administration | p | |
Population size with anosmia, n | 32 | 32 | 1 | 32 | 6 | 0.024 |
Population size with hyposmia, n | 0 | 0 | 1 | 0 | 26 | 0.024 |
Male population size with anosmia, n | 14 | 14 | 1 | 12 | 4 | 0.001 |
Male population size with hyposmia, n | 0 | 0 | 1 | 0 | 8 | 0.001 |
Female population size with anosmia, n | 18 | 18 | 1 | 20 | 2 | 0.0001 |
Female population size with hyposmia,(n,%) | 0 | 0 | 1 | 0 | 18 | 0.0001 |
Measured Sniffin' Sticks TDI olfactory scores and measured calcium levels | ||||||
---|---|---|---|---|---|---|
Pre administration | Post administration | t (2.03) | Pre administration | Post administration | t (2.03) | |
T score, mean ± SD | 2.34 ± 0.48 | 2.43 ± 0.50 | 1.79 | 2.41 ± 0.49 | 3.55 ± 0.64 | 7.97 |
D score, mean ± SD | 4.47 ± 0.42 | 4.45 ± 0.41 | 1.69 | 4.48 ± 0.43 | 6.50 ± 1.13 | 8.87 |
I score, mean ± SD | 4.29 ± 0.44 | 4.38 ± 0.45 | 1.69 | 4.39 ± 0.44 | 6.78 ± 1.16 | 10.84 |
TDI score, mean ± SD | 11.10 ± 0.99 | 11.26 ± 0.72 | 2.01 | 11.28 ± 0.79 | 16.83 ± 2.13 | 11.88 |
Nasal calcium concentration (mM), mean ± SD | 37.68 ± 1.80 | 36.40 ± 1.46 | 1.69 | 37.63 ± 2.14 | 29.18 ± 4.65 | 10.13 |
Mean ∆TDI ± SD | 0.23 ± 0.36 | 5.41 ± 2.52 | 11.25 | |||
Mean ∆ calcium concentration ± SD | 1.28 ± 1.02 | 8.44 ± 4.71 | 8.39 |