Skip to main content

Table 2 Clinically recorded results with statistical assessment before and after treatment with topical sodium chloride and TSPP

From: The effect of intra-nasal tetra sodium pyrophosphate on decreasing elevated nasal calcium and improving olfactory function post COVID-19: a randomized controlled trial

  Sodium chloride TSPP
Population size clinical assessment results
Pre administration Post administration p Pre administration Post administration p
Population size with anosmia, n 32 32 1 32 6 0.024
Population size with hyposmia, n 0 0 1 0 26 0.024
Male population size with anosmia, n 14 14 1 12 4 0.001
Male population size with hyposmia, n 0 0 1 0 8 0.001
Female population size with anosmia, n 18 18 1 20 2 0.0001
Female population size with hyposmia,(n,%) 0 0 1 0 18 0.0001
  Measured Sniffin' Sticks TDI olfactory scores and measured calcium levels
Pre administration Post administration t (2.03) Pre administration Post administration t (2.03)
T score, mean ± SD 2.34 ± 0.48 2.43 ± 0.50 1.79 2.41 ± 0.49 3.55 ± 0.64 7.97
D score, mean ± SD 4.47 ± 0.42 4.45 ± 0.41 1.69 4.48 ± 0.43 6.50 ± 1.13 8.87
I score, mean ± SD 4.29 ± 0.44 4.38 ± 0.45 1.69 4.39 ± 0.44 6.78 ± 1.16 10.84
TDI score, mean ± SD 11.10 ± 0.99 11.26 ± 0.72 2.01 11.28 ± 0.79 16.83 ± 2.13 11.88
Nasal calcium concentration (mM), mean ± SD 37.68 ± 1.80 36.40 ± 1.46 1.69 37.63 ± 2.14 29.18 ± 4.65 10.13
Mean ∆TDI ± SD 0.23 ± 0.36 5.41 ± 2.52 11.25
Mean ∆ calcium concentration ± SD 1.28 ± 1.02 8.44 ± 4.71 8.39
  1. The significant difference indicated by the bold values, values in the parenthesis are the theoretical t values