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Fig. 2 | Allergy, Asthma & Clinical Immunology

Fig. 2

From: The unique diagnostic and management challenge of a patient with concomitant anti-interferon-gamma autoantibody associated immunodeficiency syndrome, IgG4-related disease, and treatment refractory, disseminated mycobacterium avium complex infection

Fig. 2

Excisional biopsy of right axillary lymph node; A, Effacement of normal lymph node architecture by mixed inflammatory cells (H, E × 40); B, Parenchymal fibrosis (H, E × 40); C, Collection of histiocytes (H, E × 400); D, Capsular fibrosclerosis with inflammatory cells distributed in a storiform pattern (H, E × 400); E, Microabscess formation (H, E × 400); F, Positive for acid fast bacilli (AFB stain × 1000); G, IgG-positive plasma cells (immunohistochemical stain, × 100); H, IgG4-positive plasma cells focally up to 130 per high power field, IgG to IgG4 ratio about 30–40% (immunohistochemical stain × 100)

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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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